Investing.com — The recent nominations by President-elect Donald Trump, including Matt Gaetz and RFK Jr., are signaling what could be “years of chaos,” according to a note from Piper Sandler on Wednesday.

The firm’s analysts believe these appointments reflect Trump’s willingness to push congressional Republicans into difficult and potentially politically damaging positions, a strategy that could lead to significant market volatility.

Piper Sandler described the nominations as evidence of Trump’s readiness to “make congressional Republicans walk the plank.”

The firm added that these decisions signal “public policy that often won’t be friendly to financial markets.”

They note that RFK Jr.’s potential role at Health and Human Services (HHS) has already sent drug and biotech stocks into decline. However, Piper Sandler believes his confirmation is “unlikely.”

The report highlights that Trump’s controversial appointments could divide Republicans, forcing them to choose between aligning with Trump’s base or appealing to moderate voters.

The analysts said GOP senators like Susan Collins (ME) and Lisa Murkowski (AK) have already expressed reservations about some nominees.

Other Republicans, such as Thom Tillis (NC) and Bill Cassidy (LA), face re-election pressures that may influence their decisions.

The potential political fallout could extend into the 2026 midterm elections, said Pipe

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